I plan on avoiding finishing the storyline for as much as possible. My main weapons are Hunting Rifle for long range shooting. Chinese Assault Rifle for medium range. Combat Shotgun for anything close enough to smell. As a sidearm I have a laser pistol, plus a 10mm silenced pistol for when I need to be stealth. For melee I got a powerfist. I don't plan on using it unless I can't avoid it. I have a couple of backup guns of the same type if I ever need to urgently repair my weapon(s). Also carry few frag grenades and considering buying a missile launcher. I have a laser rifle but I am not sure when I will use it. Not much powerful, but I will keep it for now. I still wish there was an option for auto pause when under attack by enemy.