If you haven't already noticed, the F@H team has put up a warning for those using the GPU client: don't use the GPU client with Catalyst 7.1 drivers. Here's the post: ---------------------------- This is relevant to anyone folding with a GPU at present. The new Catalyst drivers released today 2007/01/10, version 7.1 (8.33) do not work with regard to folding on your GPU. The new drivers will cause the folding GPU core to continuously EUE on WUs, producing an "mdrun_gpu returned 114" error. The only versions of Catalyst that work with the GPU client are: 6.5 6.10 6.11 The GPU client will work with these drivers with a significant performance hit: 6.6 6.7 The following drivers do not work at all with the GPU client: 6.8 6.9 6.12 7.1 You can read the thread HERE. Edit: BTW, this would make 2 official releases that don't work with the GPU client now.